Vol. 14 No. 2 (2025): Pakistan Journal of Medicine and Dentistry

Published: 2025-04-13

Editorial

The Emergence of AI-Driven Virtual Hospitals: Redefining Patient Care Beyond Physical Boundaries

Ifrah Hameed, Hafiz Muhammad Haseeb Khaliq

1-2
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Original Article

Evaluation of Hepatic Encephalopathy Triggers and Outcomes in Chronic Liver Disease: A Regional Perspective

Mashooque Ali Samejo, Osama Ahmed, Muhammad Arsalan, Adil Hassan, Rehmat Ullah Bhatti, Ubed Ullah Bughio, Ehsan Ul Haq

3-9
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Assessing The Effectiveness of Ultrasound-Guided Injections of Steroid for Knee Osteoarthritis on Three Different Sites: A Randomized Controlled Trial Ultrasound-Guided Injections of Steroid for Knee Osteoarthritis on Three Different Sites

Ashfaque Hussain Mirjat, Imran Ahmed , Raheel Akbar Baloch, Aamir Usman Memon, Piriah Abbasi, Palwasha Abbasi
Hepcidin as a Therapeutic Target in Liver Cirrhosis: A Cohort Study on Iron Dysregulation

Arsalan Ahmed Uqaili, Adil Hassan Chang, Muhammad Amjad Kalhoro, Osama Ahmed, Mashooque Ali Samejo, Muhammad Sadik Memon, Ejaz Ahmed
Longitudinally Extensive Transverse Myelitis with Mycobacterium Tuberculosis Infection

Sameena Majeed, Rifat Ullah, Muhammad Tahir, Majeed Ullah, Ayaz Ul Haq, Arif Hayat
Impact of Maternal Age on The Rate of Caesarean Section in Induced and Spontaneous Labour

Syeda Uzma Quadri, Sumbul Sohail, Ome Kulsoom, Rehana Yasmeen, Erum Gul Sheikh
Insights to Preventive Dentistry by Evaluating Lactoferrin for Caries Control and Periodontal Disease Prevention

Rehana Kausar, Maleeha Khurram, Shaher Bano, Tahmeena Atiq, Ammara Anwar, Attique Ur Rehman, Kanwal Fatima
Steroids in Maxillofacial Space Infections: A Prospective Comparative Study

Sarmad Suleman, Ali Akhtar Khan, Sarah Bibi, Lubna Arshad Azam Raja, Ayesha Younas, Hafsa Razzaq
Post Retirement Syndrome: A Psycho-Social Perspective of The Retired Community of Pakistan

S Jamil Hussain, Fahad Ul Zain, Muhammad Iqbal Memon, Mujeeb Ullah Khan Doutani , Jamil Junejo, Sana Zain

48-54
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Periodontal Disease in Chronic Kidney Disease Patients: Implications for Systemic Health and Dental Management

Tayyaba Rafiq, Anjum Younus, Muhammad Mustafa, Suman Saeed Siddiqui, Khurram Anwar, Ravina Kumari, Kanwal Fatima, Aman Ullah Khan
Relationship Between Biochemical Parameters and Bone Mineral Density in Postmenopausal Women of Karachi, Pakistan

Madiha Soban, Razeen Fahad, Fauzia Perveen, Tahira Assad, Amina Raza, Fasiha Fatima
Expression of Salivary MMP-3 in Periodontitis Patients

Syeda Hura Anwar, Saima Sameer Quraeshi, Rehan Imad, Fizza Saher
Colorectal Cancer: Determinants of Delayed Diagnosis and Its Association with Survival in Pakistani Population

Rabia khanum , Hafiz Waqas Ahmed , Safiullah khan , Sana Tariq
Diagnostic Accuracy of Lactate Dehydrogenase and Serum Creatine Kinase to Detect Prenatal Hypoxia in Term Neonates

Sabahat Fatima, Khadija Kiran , Anas Khalil, Jazib Andleeb, Farah Naz Tahir, Zahid Mahmood
Descriptive Analysis of Cervical Insufficiency in Primigravida: Insights into Cerclage Intervention and Clinical Impact

Ayesha Saddiqa, Afshan Ambreen, Sadaf Chughtai, Sadia Ghaffar, Muhammad Awais Qarni, Zaina Tahir, Pakeeza Shafique Ul Rehman
Effects of Solanum nigrum on Liver Enzymes and Hematological Profile in Complete Freund’s Adjuvant-Induced Arthritic Rats

Haroon Ur Rasheed, Kauser Ismail, Muhammad Owais Ismail, Akhtar Ali, Humaira Arif, Sehrish Mahmood
Utility of Neutrophil-To-Lymphocyte Ratio as Prognostic Marker of Dilated Cardiomyopathy in Children

Sadaf Liaqat, Sajid Hussain Sherazi
Interplay of Heat Shock Proteins and Oxidative Stress in Modulating Neutrophil Activation in Cystic Fibrosis Inflammation

Arif Malik, Jehanzaib Islam, Anoosh Qayyum, Haleema Saadia, Gul Zaib, Ayesha Zahid
Pathological Insights into Liquid Biopsy: Role of Circulating Tumor DNA in Oral Cancer Prognosis and Therapy

Raima Kalhoro , Fatima Sarfraz , Shahzaman Memon, Ayesha Atique, Sajid Ali Majeedano , Muqaddas Fatima , Kanwal Ehsan Khan
Percutaneous Pinning for Pediatric Supracondylar Humeral Fractures: A Multicenter Evaluation

Sundas Mastoi, Zimyad Ali Mastoi, Zulfiqar Ali Mastoi
Evaluation of C-Reactive Protein and High Resolution Computed Tomography Scan Score to Initiate Early Steroid Therapy in Patients with COVID-19 Infection

Namirah Iftikhar, Muhammad Osama Rehman Khalid, Asif Husain Osmani, Gulraiz Hikmatyar, Sara Anjum Fazal
Insights to Chronic Pain in Hernia Repair: Clinicopathological Assessment of Incidence, Predictors, and Long-Term Outcomes in Tertiary Healthcare Settings

Aftab Ahmad Baig, Kaneez Aisha, Waqas Ahmad, Rizwan Khalid, Muhammad Shahid Mehmood, Shaheer Nayyar
Association of Hematological and Lipid Profile Parameters with Respiratory Functions in Class I Obese Young Adults

Salah Uddin, Farhen Malik
Rare but Possible: Three Roots with Three Canals in Maxillary First Premolars in Pakistani Subpopulation

Shaher Bano, Malik Adeel Anwar, Khadija Arif, Rai Sadaf Nawaz, Annam Aziz, Fatima Khalil
Association of Clinicopathological Parameters of Oral Squamous Cell Carcinoma with Lymph Node Metastasis

Zofeen Hashim Bhurgri, Saima Butt, Fizza Abidi, Shanzay Rehman, Sana Fatima
Analysis of Lipid Profile and Vitamin E Status in Pregnancy-Induced Hypertension

Razia Mehsud, Beenish Samreen Hamid, Summeria Jabeen Shah, Isma Rauf, Gul Muhammad , Jahangir Zaib
Implication of Different Levels of Placental Insufficiency in Predicting Perinatal Outcome

Shazia Iffet, Ayesha Arif, Sadaf Moin, Samia Ghulam Mohmmad
A Cross-Sectional Analysis for Generalized Assessment of Hernia Recovery and Complications in Tertiary Healthcare Settings

Aftab Ahmad Baig, Muhammad Shahid Mehmood, Rizwan Khalid, Samar Ghufran, Salman Majeed Chaudhry, Ali Raza

171-181
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From Skull to Identity: Cephalometric Parameters as Predictors of Stature, Sex, and Ethnicity in Pakistan

Qudsia Hassan, Marvi Masood Farooqui, Samiuddin Ahmed
Unveiling the Spectrum of Nosocomial Candiduria: A Cross-Sectional Analysis in a Tertiary Care Hospital of Punjab, Pakistan

Syed Fatima Nadeem, Muhammad Shahbaz Hussain, Farhan Rasheed, Israr Ahmad, Syed Sohail Ahmad
Ocular Injuries in Patients with Zygomaticomaxillary Complex (ZMC) Fractures at a Tertiary Care Hospital in Lahore

Muhammad Zubair Ahmad Khan, Anum Abid, Asif Shehzad, Nabeela Riaz, Tooba saeed, Syed Ahmed Rahim
Role of Epigenetic Diet on Early Menopause in Women of Karachi, Pakistan

Shaheena Hakro, Afsheen Mushtaque Shah
Articaine Outperforms Lidocaine in Maintaining Hemodynamic Stability during Dental Anesthesia

Mizhgan Khan, Sarah Khattak, Syeda Midhat Zehra, Shazia Nawaz, Tooba Riaz, Sadia Khan
Epidemiological Profile of Cancer Patients Received Radiotherapy Treatment in A Tertiary Care Teaching Hospital

Saad Jamal, Furrukh , Asma Saleem Khan, Asif Husain Osmani, Shoaib Hanif, Quratul Ain Badar, Jawaid A. Mallick
Enhancing FDG Production Efficiency on Explora FDG4 Synthesis Module: A Journey of Innovation and Excellence at Neurospinal & Cancer Care Post Graduate Institute

Syed Muhammad Haider Zaidi, Fatima Batool, Naheed Ghaffar
Comparison of Outcomes by Bipolar Electrocautery Tonsillectomy Versus Cold Steel Dissection in Pediatric Tonsillectomy

Azhar Farooq, Insa Farooq, Saba Riaz, Bilal Zahid, Aymen Farooq, Hassan Abdullah
Modified Chair Method vs. Traditional Techniques for Closed Manipulation and Relocation of Anterior Shoulder Dislocation

Muhammad Ahmad, Naseem Munshi, Athar Munir Uddin Siddiqui, Muznha Asif, Arham Azizi, Muhammad Salman Masroor
Alleviating Effects of Honey in Albino Wistar Rats with Hematological and Hepatic Variations Provoked by Methotrexate

Nadia Younus, Tayyaba Kazmi , Maniya Syed, Alina Atif, Asma Basharat Ali, Sahrish Mukhtar, Ruqaya Nangrejo
Estimation of Heavy Metals in Pakistani and International Branded Canned Foods in the Markets of Peshawar, Khyber Pakhtunkhwa, Pakistan

Shaista Nooreen, Kashif Ur Rehman Khalil, Rozina Rehman, Sarfaraz Khan Afridi, Baber Awan, Azra Shaheen
Predictive Factors of Fatal Bleeding in Pediatric Acute Promyelocytic Leukemia (APL)

Rabiha Manzoor, Fozia Sayed Rasool, Qurratulain Ali, Fahd Rashid, Ajaz Ahmed, Iqra Tariq
Association Between Body Mass Index and Low Back Pain: A Retrospective Observational Study

Shahzaib Riaz Baloch , Muhammad Tariq Sohail, Mohammad Sohail Rafi, Adnan Aqueel Lokhandwala, Eamaan Abid, Faryal Karim
A Comparative Study on Low Back Pain with Radiculopathy treated with Conventional NSAIDs versus Combination of Caudal Epidural Steroid Injections and NSAIDs

Imran Manzoor , Rizwan khan, Mohammad Usman Sarwar, Muhammad Usama Athar, Muhammad Omer Imran, Fahad Usman
Non-Sonographic Hydrostatic Reduction of Intussusception in Children in Underdeveloped Pakistan

Majid Arshad, Anum Fatima, Rahmat Ali Khan, Khawar Saeed, Bakht Sarwar
Quantitative Evaluation of Forensic Odontology Competency: Implications for Community Dentistry: A Curriculum Assessment Survey

Wajiha Anzar, Talal Bin Taheer, Muhammad Bilal Bashir, Syed Jaffar Abbas Zaidi
Clinical Predictors of Severe Dengue

Qurrat-Ul-Ain Usmani, Jameel Muqtadir, Yousra Arshad, Hudaubiya Ayub
Vascular Adaptations in Pregnancy: The Critical Role of Endothelial Function and Nitric Oxide in Maternal-Fetal Health

Hina Riaz, Urooj Bhatti, Keenjher Rani, Afsheen Abro, Rabia Uqaili, Rubina Ahmdani
Frequency of In-Hospital Mortality in Patients with Upper Gastrointestinal Bleeding (UGIB) Due to Liver Cirrhosis

Mehwish Dilber, Abdul Aziz Sahito, Waseem Raja Memon, Zafarullah Phul, Muhammad Zarrar, Riaz Hussain Khokhar
Cross-Sectional Evaluation of Hydroxyapatite-Coated Titanium Implants: Insights into Biocompatibility and Osseointegration

Tayyaba Rafiq, Iqra Amin, Atiq Ur Rehman, Amna Mehwish Ikram, Khurram Anwar, Arsalan Ahmed, Ayesha Ali Khawaja

315-320
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Salivary Basic Fibroblast Growth Factor Expression: A Gateway to Early Detection of Oral Submucous Fibrosis

Shafaq Saeed Roghay, Afifa Razi, Hira Batool, Saima Akram Butt, Fizza Abidi, Saima Sameer Qureshi

321-326
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Frequency of Surgical Site Infection in Patients Undergoing Exploratory Laparotomy in Tertiary Care Hospital, Karachi

Shireen Sabir Ansari , Shakila, Maida Naeem, Alhamad Mustafa, Zainab Ashraf, Mehwish Mooghal

327-333
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Serum FGF-23 and Vitamin D Deficiency as Predictors of Metabolic Syndrome in Chronic Kidney Disease

Tazeen Shah, Arsalan Ahmed Uqaili, Saima Naz Shaikh, Salahuddin Shaikh Madni, Rizwan Channa, Hira Saeed Khan

334-341
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Gingival Zenith Variations in Maxillary Anterior Teeth Across Age and Gender in the Pakistani Population

Alina Shahiryar, Rija Anees, Muhammad Aamir Ghafoor Chaudhary, Sadaf Shafique, Parivash Anwar

342-352
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In-Vitro Exploration of Silver Nanoparticle Coatings: Novel Insights to Biocompatibility and Antimicrobial Properties

Waqas Memon, Irum Naz, Muhammad Mustafa, Amna Mehwish Ikram, Agha Taymoor Ali, Permanand, Ayesha Sanaullah Khan, Ayesha Imtiaz

353-357
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Complex Hip Arthroplasty Following Failed Proximal Femur Osteosynthesis

Shahzaib Riaz Baloch, Mohammad Sohail Rafi, Syed Ata Ur Rahman, Imtiaz Ahmed Hashmi, Eamaan Abid, Faryal Karim

358-365
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Platelet Concentrate Utilization Trends in a Tertiary Care Hospital: A Comprehensive Analysis

Aamir Ramzan, Muhammad Sarwar Khan, Abid Hussain Chang, Bakhtawar Akbar, Shabnam Ansari, Kiran Memon

367-372
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Exploring Cardio-Physician's Clinical Challenges and Outcomes in Managing Multimorbid Cardiac Patients by Cross-Sectional Analysis

Ansa Rehman, Jaweria Amjad Memon, Baloch Zaman, Muhammad Hassan Butt, Muhammad Ismail, Kheraj Mal, Muhammad Arsalan Shah

373-377
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Meta Analysis

Prevalence of Toxoplasmosis in Blood Donors: A Systematic Review and Meta-Analysis

Amna Iqbal Butt, Ammara Riaz, Fariha Salman, Laila Afzal, Sana Qanber Abbasi, Rabiah Mahwish

378-390
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The Effectiveness of Sub-Threshold Laser Versus Spironolactone for The Treatment of Central Serous Chorioretinopathy: A Systematic Review and Meta-Analysis

Amber Khalid, Aveen Fatima, Quratulain Saleem

391-401
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Systematic Review

Assessment of Matrix Metalloproteinases a Prognostic Indicator in Advanced Fibrotic Lung Disease: A Systematic Review

Mehvish Aqil, Saif Ur Rahman, Muhammad Zeeshan Aslam, Mostafa Ahmed Abdellah Ahmed, Ammar Ahmed, Sidra Javaid, Ehsan Ul Haq

402-412
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Physiological Insights into Pregnancy-Associated Bone Metabolism: A Systematic Review of Vitamin D and Parathyroid Hormone Axis

Aqsa Naeem, Rabia Zuhaib, Abdul Rehman Khalil Shaikh, Pashmina Shaikh, Muhammad Amjad Kalhoro, Shabnam, Pakeeza Shafique Ul Rehman

413-422
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Maternal-Fetal Endocrine Interface: A Systematic Review of the Clinicopathological Assessment of Hypothalamic-Pituitary-Adrenal Axis Dysregulation in Pregnancy Complications

Fatima Bibi, Ome Kulsoom, Maria Khalid, Shama Chaudhry, Rehana Yasmeen, Shazia Sultana, Aneesa Khalid

423-431
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Comparative Analysis and Systematic Review of Nanocomposite Resins in Restorative Dentistry: Durability and Antimicrobial Properties

Muhammad Saleem Qureshi, Khadija Akhtar, Farah Tasleem, Permanand, Maleeha Khurram, Ayesha Imtiaz, Muhammad Hussain

432-441
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Clinicopathological Assessments of Brain-Derived Neurotrophic Factor BDNF Physiology in Diabetic Retinopathy: A Systematic Review

Raima Kalhoro, Raffad, Muhammad Usman Durrani, Abdul Munim, Nazish Jamil, Muhammad Imran Ali, Muhammad Arsalan Shah

442-451
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A Systematic Review on Histopathological and Molecular Biomarkers in Oral Pathology: Advancing Early Diagnosis of Precancerous and Cancerous Lesions

Mostafa Ahmed Abdellah Ahmed, Madeeha Minhas, Uzma Tariq, Dinesh Kumar, Muhammad Mazhar, Mohammed Faisal, Ejaz Ahmed

452-462
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Effect of Incorporation of Bioactive Agents in Dentin Bonding Agent on Bond Strength: A Systematic Review

Usama Wasi Ullah , Nida Zehra Bano, Muhammad Omar Niaz, Mehmood Asghar Bhatti

463-485
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Evaluating The Effectiveness of Nefopam Versus Tramadol in Treating Established Post-Spinal Anesthesia Shivering: A Systematic Review

Ahsan Amjad, Usman Khalid, Adil Ashraf, Sumayya Tariq, Akrama Ehsan, Syed Imtiaz Ali Zaidi, Muhammad Hussain

486-495
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A Systematic Review on Clinicopathological Evaluation of Neutrophil-Percentage-To-Albumin-Ratio (NPAR): An Emerging Biomarker for Hepato-Pathology and Hepato-Oncology

Abdul Rehman Khalil Shaikh, Abdul Mannan Jehangir, Anum Usman, Durga Devi, Muhammad Akram, Muhammad Mazhar

496-504
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A Systematic Review on Insights to Community Medicine and Clinical Research: Competency Training in Medical and Dental Education

Madeeha Minhas, Bilal Masood, Muhammad Hassaan Saeed, Amna Iqbal Butt, Fareed Ud Din Ahmad Chishti, Fatima Ali

505-514
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Molecular Insights to Adiponectin in Pregnancy Pathologies: A Systematic Review on Physiological and Clinical Pathological Perspective

Saima Naz Shaikh, Noor Un Nisa Memon, Rabia Zuhaib, Padma Rathore, Tallat Naz, Pashmina Shaikh, Aneesa Khalid

515-523
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Dental Education

Comparative Analysis of Integrated OSPE Versus Conventional OSPE in Assessing First-Year BDS Students’ Competence

Fatima Shaukat , Rizwan Sultan, Saba Farooq, Aeman Choudhary, Saman Mailk, Alina Qamar

524-529
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Case Report

Chameleons of Multiple Sclerosis: A Case Series

Ayesha Abdul Samad, Saba Zaidi, Syeda Areeba Tabassum, Mahzareen Ishrat

530-535
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Surgical Management of Testicular Sarcoma: A Case Report

Muhammad Ahmed Aftab, Zahra Saifuddin Rajbhoy, Kainat Islam, Yasir Murtaza, Anis Hussain Jaffery

534-540
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The Life-Saving Impact of Early Diagnosis and Treatment for Spinal Muscular Atrophy Type 1

Almas Siddique, Shanzay Siddique, Erum Akhter

541-545
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Letter to the Editor

Male Postpartum Depression: A Neglected Issue in Pakistan

Shaharyar Usman, Abhishek Lal

546-547
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The Alarming State of Hepatitis B Vaccination Among Dentists: Local, National and Global Implications

Muhammad Usman Sultan, Ihsan Ullah, Muhammad Anas

548-549
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Revumenib as A New Therapeutic Intervention for Relapsed or Refractory KMT2A-Rearranged Acute Lymphoblastic Leukemia

Khushbakht Baloch, Muniba Shoaib, Mishal Fatima

550-551
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