Non-Sonographic Hydrostatic Reduction of Intussusception in Children in Underdeveloped Pakistan

Authors

DOI:

https://doi.org/10.36283/ziun-pjmd14-2/043

Keywords:

Intussusception, Intestinal Obstruction, Hydrostatic Reduction, Enema Techniques, Radiographic Methods, Pediatric Gastroenterology, Pediatrics, Ileocolic Intussusception, Non-Imaging Techniques, Child Health

Abstract

Background: Intussusception is a significant cause of pediatric intestinal obstruction that requires rapid intervention. While ultrasound-guided hydrostatic reduction is the standard treatment in developed healthcare systems, its availability is limited in resource-limited settings. This study evaluated the efficacy and safety of non-sonographic-guided hydrostatic reduction for the treatment of pediatric intussusception in a resource-limited setting in Pakistan.

Methods: A prospective descriptive case series study was conducted between January 2022 and January 2024 at Timergara Teaching Hospital involving 120 children aged 6 months to 3 years with ultrasound-confirmed acute ileocolic intussusception. A consecutive sampling technique was used to include all eligible patients during the study period. Success rates were analyzed for different age groups and symptom durations. Data analysis was conducted using IBM SPSS Statistics v20.0. Continuous variables were presented as mean ± SD or median (IQR), while categorical variables were shown as frequencies and percentages. Chi-square tests analyzed categorical data, and stratification by age, symptom onset, clinical signs, and vital signs minimized confounders. Statistical significance was set at p < 0.05.

Results: The overall success rate of hydrostatic reduction was 90.0% (n=108). Male patients accounted for 68 (56.7%) cases. The highest success rates were observed in children aged 7-12 months (n= 45; 91.8%) and in cases treated within 6-12 hours of symptom onset (n= 67; 95.7%). Success rates decreased significantly with increasing duration of symptoms, dropping to 10 (76.9%) cases treated after 24 hours (p=0.035). The most common symptoms were abdominal pain (n=112; 93%), fever (103; 86%), and a palpable abdominal mass (95; 79%).

Conclusion: Non-sonographic guided hydrostatic reduction is a highly effective treatment for uncomplicated pediatric intussusception in resource-limited settings, especially when performed within 12 hours of symptom onset. Early intervention is critical for optimal outcomes.

 

Author Biographies

  • Majid Arshad, DHQ Teaching Hospital Timergara Lower Dir, KPK, Pakistan

    Pediatric Surgery Unit

  • Anum Fatima, Al-Sehat Medical Complex, Timergara Lower Dir KPK, Pakisan.

    Department of Surgery,

     

     

  • Rahmat Ali Khan, Peads Surgery and Peads Urology Unit, PAQSJIMS Gambat Sindh

    Department of Peadiatric Surgery and Peadiatric Urology,

  • Khawar Saeed, Northwest General Hospital Peshawar, KPK

    Department of Pediatric Surgery ,

  • Bakht Sarwar, DHQ Teaching Hospital Timergara Lower Dir KPK

    Department of Surgery, 

     

     

References

Toussaint TW, Wandaogo A, Yaméogo W IC, Ouédraogo I, Ouédraogo SMF, Zampou O, Béré B, Aliabadi N, Leshem E, Nikièma M, Ouattara M, Mwenda JM, Bonkoungou I, Bandré E, Parashar UD, Tate JE. Acute intestinal intussusception among children under five years of age admitted in an Ouagadougou hospital, Burkina Faso, 2008-2013: epidemiological, clinical and therapeutic aspects. Pan Afr Med J. 2021 Jul 28;39(Suppl 1):5. doi: 10.11604/pamj.supp.2021.39.1.25270.

Cheikhrouhou T, Chtourou R, Ben Dhaou M, Mallouli M, Benkraiem N, Kallel R, Ammar S, Zitouni H, Boudawara TS, Mhiri R. Intestinal tumor lesions leading to intussusception in children: a report of four cases and literature review. Annals of Pediatric Surgery. 2022 Nov 22;18(1). doi: 10.1186/s43159-022-00213-z

Martin JE, Capleton P. Neuromuscular and mechanical disorders of the small bowel. Morson and Dawson's Gastrointestinal Pathology. 2024 Sep 16:385-96. Doi: 10.1002/9781119423195.ch19

Reschke P, Le Hong QA, Gruenewald LD, Gotta J, Koch V, Höhne E, Mahmoudi S, Juergens LJ, Hescheler DA, Bucher AM, Biciusca T. Malignancy predictors and treatment strategies for adult intestinal intussusception. Academic Radiology. 2024 Oct 22; 12. DOI: 10.1055/a-2434-7932

Hwang J, Yoon HM, Kim PH, Jung AY, Lee JS, Cho YA. Current diagnosis and image-guided reduction for intussusception in children. Clin Exp Pediatr. 2023 Jan;66(1):12-21. doi: 10.3345/cep.2021.01816.

Morais SM, Costa CS, Mourato MB, Mogne T, Santos G. Intestinal intussusception: a shocking diagnosis. Cureus. 2022 May;14(5). doi: 10.7759/cureus.25368

Wang L, Zhang H, Wang D, Shen Q, Huang L, Liu T. Clinical features of intussusception in children secondary to small bowel tumours: a retrospective study of 31 cases. BMC Pediatrics. 2024 Apr 1;24(1):227. DOI: 10.1186/s12887-024-04717-y

Ayyanar P, Behera G, Mishra TS, Purkait S, Patra S, Mitra S. The clinico-histopathological spectrum of tumors and tumor-like lesions in adult intussusception. Journal of Gastrointestinal Cancer. 2022 Sep;53(3):511-9. DOI: 10.1007/s12029-021-00647-5

Al Ammari N, Lampus H, Kurniawan A. Intussusception: Diagnosis and Management According to the Competence of Primary Service Doctors. e-CliniC. 2022 Mar 31;10(1):145-50. DOI: https://doi.org/10.35790/ecl.v10i1.37464

Lee EH., Yang HR. Nationwide population-based epidemiologic study on childhood intussusception in South Korea: emphasis on treatment and outcomes. Pediatr Gastroenterol Hepatol Nutr: 2020;23:329–45. doi: 10.5223/pghn.2020.23.4.329

Kim KH. Intussusception in adults: a retrospective review from a single institution. Open Access Emergency Medicine. 2021 Jun 14:233-7. DOI: 10.2147/OAEM.S313307

Coelho LS, Rocha-Santos V, Faintuch J. Options on Conservative Treatment in Acute Surgical Emergencies. In Acute Care Surgery in Geriatric Patients 2023 Aug 4 (pp. 379-387). Cham: Springer International Publishing.

American College of Radiology. ACR-SPR practice parameter for the performance of pediatric fluoroscopic contrast enema examinations [Internet]. Reston (VA): American College of Radiology; [revised 2021; cited 2021 Oct 17]. Available from: https://www.acr.org/-/media/ACR/Files/Practice-Parameters/FluourConEnema-Ped.pdf.

Arshad M, Fatima A, Imran M, Khan RA, Ullah M. Postoperative Outcomes In Children With Typhoid Ileal Perforation: Primary Repair Versus Ileostomy. Journal of Population Therapeutics and Clinical Pharmacology. 2024 Jul 9; 31(7):296-301. DOI: https://doi.org/10.53555/jptcp.v31i7.6949

Fiordaliso M, Panaccio P, Costantini R, De Marco AF. Comparison between children and adults with intussusception. Description of two cases and review of literature. Annali Italiani di Chirurgia. 2021 May 1;92(3):268-76. https://annaliitalianidichirurgia.it/index.php/aic/article/view/1306.

Clark AD, Hasso-Agopsowicz M, Kraus MW, Stockdale LK, Sanderson CF, Parashar UD, Tate JE. Update on the global epidemiology of intussusception: a systematic review of incidence rates, age distributions, and case-fatality ratios among children aged< 5 years, before the introduction of rotavirus vaccination. International journal of epidemiology. 2019 Aug 1;48(4):1316-26. DOI: https://doi.org/10.1093/ije/dyz028

Brill A, Lopez RA. Intussusception in Adults. [Updated 2023 Aug 7]. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK545264/

Tseng WY, Chao HC, Chen CC, Lai MW, Chang YJ. Adenovirus infection is a risk factor for recurrent intussusception in pediatric patients. Pediatrics & Neonatology. 2023 Jul 1;64(4):428-34. DOI: https://doi.org/10.1016/j.pedneo.2022.03.024

Ye X, Tang R, Chen S, Lin Z, Zhu J. Risk factors for recurrent intussusception in children: a systematic review and meta-analysis. Frontiers in pediatrics. 2019 Apr 16;7:145. DOI: https://doi.org/10.3389/fped.2019.00145

Bandaranayake GK, Erandika H, Hettiarachchi M. The success of ultrasound-guided hydrostatic reduction in managing delayed presentation of childhood intussusception: A single center experience. Journal of Pediatric Surgery Open. 2023 Dec 1;4:100073. DOI: https://doi.org/10.1016/j.yjpso.2023.100073

Wondemagegnehu BD, Kerego EN, Mammo TN, Robele AT, Gebru FT, Aklilu WK. Predictors of Failure in Ultrasound-Guided Hydrostatic Reduction of Intussusception in Children: Retrospective Analysis in a Specialized Center in Ethiopia. Pediatric Health, Medicine and Therapeutics. 2024 Dec 31:87-94. DOI https://doi.org/10.2147/PHMT.S451832

Belkind-Gerson J. Intussusception. Gastrointestinal Disorders in Neonates and Infants. Sept 2023. Available at: https://www.msdmanuals.com/professional/pediatrics/gastrointestinal-disorders-in-neonates-and-infants/intussusception

Davarpanah AH, Ghamari Khameneh A, Khosravi B, Mir A, Saffar H, Radmard AR. Many faces of acute bowel ischemia: overview of radiologic staging. Insights into Imaging. 2021 Apr 29;12(1):56. DOI: 10.1186/s13244-021-00985-9

Lendzion RJ, Frahm-Jensen G, Keck J. Acute Mesenteric Ischemia. Clin Colon Rectal Surg. 2022 Aug 12;35(3):227-236. doi: 10.1055/s-0042-1743283. doi: 10.1055/s-0042-1743283

Elsharkawy NM, Abu Zeid MM, Ahmed ME, Attia SM. Clinical predictors of mortality in acute mesenteric ischemia. The Egyptian Journal of Hospital Medicine. 2021 Jan 1;82(3):479-86. https://ejhm.journals.ekb.eg/article_146981_f35047224e38647ede9bba12c5753398.pdf

Boeddha NP, Meijer NI, van Heesch G. Intussusception presenting with fluctuating mental status changes. Journal of Pediatric Surgery Case Reports. 2021 Sep 1;72:101948. DOI: https://doi.org/10.1016/j.epsc.2021.101948

Ali K, Sekkat H, Mehdi B, Raiss M, Sabbah F, Hrora A. The management of colo-colic intussusception on left colon tumor in an adult: Case presentation and review of the literature. International Journal of Surgery Case Reports. 2024 Nov 10:110578. DOI: https://doi.org/10.1016/j.ijscr.2024.110578

Ashraf A, Amer M, Walizai T, et al. Intussusception. Radiopaedia. 7 Nov 2024. (Accessed on 23 Dec 2024). DOI: https://doi.org/10.53347/rID-1526

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Published

2025-04-13

How to Cite

1.
Arshad M, Fatima A, Khan RA, Saeed K, Sarwar B. Non-Sonographic Hydrostatic Reduction of Intussusception in Children in Underdeveloped Pakistan. PJMD [Internet]. 2025 Apr. 13 [cited 2025 Jul. 10];14(2):280-6. Available from: https://ojs.zu.edu.pk/pjmd/article/view/3379

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