Cross-Sectional Evaluation of Hydroxyapatite-Coated Titanium Implants: Insights into Biocompatibility and Osseointegration

Authors

  • Tayyaba Rafiq College of Dentistry, Lahore Medical and Dental College, Lahore,Pakistan.
  • Iqra Amin Muhammad Islam Dental College ,Gujranwala, Pakistan.
  • Atiq Ur Rehman Institute of Dentistry (IOD) CMH Lahore Medical College, Lahore Cantt,Pakistan.
  • Amna Mehwish Ikram Islam Medical and Dental College, Sialkot. Pakistan
  • Khurram Anwar Isra Dental College ,Isra university Hyderabad Sindh, Pakistan
  • Arsalan Ahmed Bhitai Dental & Medical College, Mirpurkhas Sindh, Pakistan.
  • Ayesha Ali Khawaja Baqai Medical University, Karachi, Pakistan.

DOI:

https://doi.org/10.36283/ziun-pjmd14-2/048

Keywords:

Hydroxyapatites, Titanium, Implant, Osseointegration, Biocompatibility, Dental Implant Stability

Abstract

Background: The application of hydroxyapatite (HA) coatings represents a powerful method for improving the biorientation of titanium dental implants and their compatibility with human tissue. The research examined the consequences of applying HA coatings on dental implant integration while investigating bone tissue response in the nearby area.

Methods: In this cross-sectional collaborative study conducted mainly at Baqai Medical University, Lahore Medical and Dental College and Muhammad Islam Dental College, eighty patients (BMU-EC/006-22) (average age 55.3 ± 8.7 years) participated in the assessment during the period from August 2022 to December 2023 based on a purposive sampling technique. The evaluation of implant stability, together with peri-implant bone density and inflammatory response markers, constituted the clinical measurement criteria. Professionals used both patient evaluations and imaging data to evaluate the efficiency of osseointegration. The analysis of data occurred through SPSS version 20 using one way ANOVA with p-value<0.05, statistically significant. Research findings for HA-coated versus uncoated implants derived from independent t-tests for continuous variables and chi-square tests for categorical data.

Result: The study outcomes revealed that implants coated with HA exhibited better bone attachment to implant surfaces, enhanced implant stability (p = 0.012), and decreased inflammation markers (p = 0.018). Under histological examination, there was improved contact between bone tissue and the implant surface, which proves that HA contributes to quick osseointegration.

Conclusion: The implant recipients with HA coatings experienced fewer complications and better outcomes in terms of functionality.

Author Biographies

  • Tayyaba Rafiq, College of Dentistry, Lahore Medical and Dental College, Lahore,Pakistan.

    Department of Oral and Maxillofacial surgery,


  • Iqra Amin, Muhammad Islam Dental College ,Gujranwala, Pakistan.

    Department of Oral Biology


  • Atiq Ur Rehman, Institute of Dentistry (IOD) CMH Lahore Medical College, Lahore Cantt,Pakistan.

    Department of Prosthodontics,


  • Amna Mehwish Ikram, Islam Medical and Dental College, Sialkot. Pakistan

    Department of Dental Materials,


  • Khurram Anwar, Isra Dental College ,Isra university Hyderabad Sindh, Pakistan

    Department of Periodontology, 

  • Arsalan Ahmed, Bhitai Dental & Medical College, Mirpurkhas Sindh, Pakistan.

    Department of Periodontics,

  • Ayesha Ali Khawaja, Baqai Medical University, Karachi, Pakistan.

    Department of Dentistry,

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Published

2025-04-13

How to Cite

1.
Rafiq T, Amin I, Rehman AU, Ikram AM, Anwar K, Ahmed A, et al. Cross-Sectional Evaluation of Hydroxyapatite-Coated Titanium Implants: Insights into Biocompatibility and Osseointegration. PJMD [Internet]. 2025 Apr. 13 [cited 2025 Jul. 10];14(2):315-20. Available from: https://ojs.zu.edu.pk/pjmd/article/view/3574

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