Association Between Body Composition Characteristics and Pulmonary Function Parameters in Young Adults of Shaheed Benazirabad District

Hajira Naila; Zulfiqar Ali Laghari

doi:10.36283/ziun-pjmd14-1/004

Authors

Hajira Naila Peoples University of Medical and Health Sciences for Women, Nawabshah, Shaheed Benazirabad, Sindh, Pakistan. https://orcid.org/0009-0003-8873-0250
Zulfiqar Ali Laghari Peoples University of Medical and Health Sciences for Women, Nawabshah, Shaheed Benazirabad, Sindh, Pakistan.

DOI:

https://doi.org/10.36283/ziun-pjmd14-1/004

Keywords:

Body Mass Index, Pulmonary function, Obesity, Vital Capacity

Abstract

Background: Obesity is a significant global health issue linked to increased risks of respiratory diseases. This study examines the association between body composition metrics, such as Body Mass Index (BMI) and Waist-to-Hip Ratio (WHR), and lung function in adults aged 20-40 years.

Methods: A cross-sectional analysis was conducted at the Physiology Department of Peoples University of Medical and Health Sciences from February 2023 to April 2024, involving 376 adults. Participants were categorized based on their BMI and evaluated for WHR. Pulmonary function was assessed using spirometry, following American Thoracic Society guidelines. Statistical analysis was performed with SPSS version 27, utilizing Pearson’s correlation coefficient and the chi-square test, with a p-value <0.05 considered significant.

Results: The sample consisted of 236 (62.8%) males and 140 (37.2%) females, with a mean age of 31.39±6.35 years. The mean BMI was 23.65±3.95 kg/m². Overweight individuals accounted for 220 (58.5%), and obesity for 85 (22.6%). Of the sample, 258 (68.6%) had reduced Vital Capacity (VC), 250 (66.5%) had decreased Total Lung Capacity (TLC), and 243 (64.6%) had decreased Forced Vital Capacity (FVC). A negative correlation was found between BMI and VC (p<0.001), as well as between WHR and VC.

Conclusion: Increased BMI and WHR are associated with respiratory function impairment. Weight loss and improved body composition may enhance respiratory health and reduce cardiovascular disease risk.

Author Biographies

Hajira Naila, Peoples University of Medical and Health Sciences for Women, Nawabshah, Shaheed Benazirabad, Sindh, Pakistan.

Professor, Department of Physiology
Zulfiqar Ali Laghari, Peoples University of Medical and Health Sciences for Women, Nawabshah, Shaheed Benazirabad, Sindh, Pakistan.

Chairman, Department of Physiology

References

Dixon AE, Peters U. The effect of obesity on pulmonary function. Expert Rev Respir Med. 2018 Sep;12(9):755-67. doi: 10.1080/17476348.2018.1506331.

Chen XF, Yan LJ, Lecube A, Tang X. Diabetes and obesity effects on pulmonary function. Front Endocrinol. 2020 Jul;11:564636. doi: 10.3389/fendo.2020.00462.

He H, Wang B, Zhou M, Cao L, Qiu W, Mu G, Chen A, Yang S, Chen W. Systemic inflammation mediates the associations between abdominal obesity indices and pulmonary function decline in a Chinese general population. Diabetes Metab Syndr Obes. 2020 Jan;13:141-50. doi: 10.2147/DMSO.S229749.

Liu J, Xu H, Cupples LA, O’Connor GT, Liu CT. The impact of obesity on pulmonary function measurements and respiratory disease: A Mendelian randomization study. Ann Hum Genet. 2023 Jul;87(4):174-83. doi: 10.1111/ahg.12506.

Peralta GP, Marcon A, Carsin AE, Abramson MJ, Accordini S, Amaral AF, Antó JM, Bowatte G, Burney P, Corsico A, Demoly P, Dharmage S, Forsberg B, Fuertes E, Garcia-Larsen V, Gíslason T, Gullón JA, Heinrich J, Holm M, Jarvis DL, Janson C, Jogi R, Johannessen A, Leynaert B, Rovira JM, Nowak D, Probst-Hensch N, Raherison C, Sánchez-Ramos JL, Sigsgaard T, Siroux V, Squillacioti G, Urrutia I, Weyler J, Zock JP, Garcia-Aymerich J. Body mass index and weight change are associated with adult pulmonary function trajectories: the prospective ECRHS study. Thorax. 2020 Apr;75(4):313-20. doi: 10.1136/thoraxjnl-2019-213880.

Krol KA, Litonjua AA. Beyond obesity: The complex relationship between early growth trajectories and later pulmonary function. J Allergy Clin Immunol. 2021 Sep;148(3):713-5. doi: 10.1016/j.jaci.2021.07.009.

Hall GL, Filipow N, Ruppel G. Official ERS technical standard: Global Pulmonary Function Initiative reference values for static lung volumes in individuals of European ancestry. Eur Respir J. 2021 Mar;57(3). doi: 10.1183/13993003.00289-2020.

Marillier M, Bernard AC, Reimao G, Castelli G, Alqurashi H, O'Donnell DE, Neder JA. Breathing at extremes: the restrictive consequences of super-and super-super obesity in men and women. Chest. 2020 Oct;158(4):1576-85. doi: 10.1016/j.chest.2020.04.006.

Liu P, Ye Z, Lu H, Lu J, Huang L, Gong J, Deng Q, Xu L. Association between body mass index (BMI) and vital capacity of college students of Zhuang nationality in China: a cross-section study. Oncotarget. 2017 Oct;8(46):80923. doi: 10.18632/oncotarget.20758.

Miethe S, Karsonova A, Karaulov A, Renz H. Obesity and asthma. J Allergy Clin Immunol. 2020 Oct;146(4):685-93. doi: 10.1016/j.jaci.2020.08.011.

Bantulà M, Roca-Ferrer J, Arismendi E, Picado C. Asthma and obesity: two diseases on the rise and bridged by inflammation. J Clin Med. 2021 Jan;10(2):169. doi: 10.3390/jcm10020169.

Jansang S, Eksakulkla S. The Effect of a Breathing Training Program using a Toy Blower on Lung Function, Respiratory Muscles Strength, 6-Minute Walking Test, and Functional Capacity in Obesity Level 2. J Exerc Physiol Online. 2023 June;26(3). doi: 10.58837/CHULA.THE.2022.306.

Ogata H, Nakano H, Yanagihara T, Moriuchi Y, Enokizu-Ogawa A, Ishimatsu A, Otsuka J, Furukawa T, Taguchi K, Moriwaki A, Yoshida M. Preserved ratio impaired spirometry and severity of obstructive sleep apnea: An observational cross-sectional study. Respir Med. 2024 Nov;234:107806. doi: 10.1016/j.rmed.2024.107806.

Abd-Elaleem NA, Mohamed SAA, Wagdy WM, Abd-Elaleem RA, Abdelhafeez AS, Bayoumi HA. Changes in spirometric parameters with position in asymptomatic Egyptian young males with central obesity. Multidiscip Respir Med. 2021 Jan;16(1). doi: 10.4081/mrm.2021.745.

Yousif AO, Merghani TH, Alawad AO. Body Mass Index and Body Fat Percentage for the Assessment of Obesity-Induced Abnormalities in Dynamic Lung Volumes. Saudi J Nurs Health Care. 2022 Feb;5(2):32-5. doi: 10.36348/sjnhc.2022.v05i02.003.

Marillier M, Bernard AC, Reimao G, Castelli G, Alqurashi H, O'Donnell DE, Neder JA. Breathing at extremes: the restrictive consequences of super-and super-super obesity in men and women. Chest. 2020 Oct;158(4):1576-85. doi: 10.1016/j.chest.2020.04.006.

Arismendi E, Bantulà M, Perpiñá M, Picado C. Effects of obesity and asthma on pulmonary function and airway dysanapsis in adults and children. J Clin Med. 2020 Nov;9(11):3762. doi: 10.3390/jcm9113762.

Forno E, Han YY, Mullen J, Celedón JC. Overweight, obesity, and pulmonary function in children and adults—a meta-analysis. J Allergy Clin Immunol Pract. 2018 Mar;6(2):570-81. doi: 10.1016/j.jaip.2017.07.010.

Brock JM, Billeter A, Müller-Stich BP, Herth F. Obesity and the lung: what we know today. Respiration. 2021 Nov;99(10):856-66. doi: 10.1159/000509735.

De Soomer K, Vaerenberg H, Weyler J, Pauwels E, Cuypers H, Verbraecken J, Oostveen E. Effects of weight change and weight cycling on pulmonary function in overweight and obese adults. Ann Am Thorac Soc. 2024 Jan;21(1):47-55. doi: 10.1513/AnnalsATS.202212-1026OC.

Tang Y, Zhang L, Zhu S, Shen M, Cheng M, Peng F. Associations between different body mass index and pulmonary function impairment in Chinese people aged over 40 years: a multicenter cross-sectional study. BMC Pulm Med. 2024 Jan;24:30. doi: 10.1186/s12890-024-02844-x.

Keogh E, Williams ME. Managing malnutrition in COPD: a review. Respir Med. 2021 Jan;176:106248. doi: 10.1016/j.rmed.2020.106248.

Grigsby MR, Siddharthan T, Pollard SL, Chowdhury M, Rubinstein A, Miranda JJ, Bernabe-Ortiz A, Alam D, Kirenga B, Jones R, van Gemert F, Checkley W. Low body mass index is associated with higher odds of COPD and lower pulmonary function in low- and middle-income countries. COPD. 2019 Jan;16(1):58–65. doi: 10.1080/15412555.2019.1589443.

Svartengren M, Cai GH, Malinovschi A, Theorell-Haglöw J, Janson C, Elmståhl S, Lind L, Lampa E, Lindberg E. The impact of body mass index, central obesity and physical activity on pulmonary function: results of the EpiHealth study. ERJ Open Res. 2020 Oct;6(4):00214–2020. doi: 10.1183/23120541.00214-2020.

Fu C, Yang H. Association between appendicular lean mass and chronic obstructive pulmonary disease: epidemiological cross-sectional study and bidirectional mendelian randomization analysis. Front Nutr. 2023 Jun;10:1159949. doi: 10.3389/fnut.2023.1159949.

Dailah HG. Therapeutic potential of small molecules targeting oxidative stress in the treatment of chronic obstructive pulmonary disease (COPD): a comprehensive review. Molecules. 2022 Aug;27(17):5542. doi: 10.3390/molecules27175542.