LIPIDS LEVELS COMPARISON OF DIABETIC AND NON-DIABETIC INDIVIDUALS: A RETROSPECTIVE STUDY AT A SECONDARY CARE HOSPITAL
Keywords:
Metabolic diseases, diabetes mellitus, dyslipidemias, lipids, glycated hemoglobin, healthy lifestyleAbstract
Background of the Study: Diabetes mellitus, a chronic metabolic disorder is linked with various consequences among which cardiovascular diseases tops the list. Dyslipidemia is one of the most common conditions signifying the level of risk of cardiovascular events. Understanding the differences in different profiles of lipid can not only provide insight but will also help in designing new protocols for rehabilitation interventions and management of risk factors using such interventions. Thus, the aim is to compare the comparison of lipid levels between diabetic and non-diabetic individuals at a secondary care hospital in Karachi, Pakistan.
Methodology: The study included total 158 patients. We divided them into two groups on the basis of diabetes. There were 103 diabetic patients with mean HbA1C 12.2% ± 23.8. The control group which was non-diabetic had 55 subjects with mean HbA1C of 5.3% ± 0.26. Lipid profile results were evaluated.
Results: The results showed that the diabetic group had mean values for Total cholesterol (TC) was 188.8 ± 50.1, Triglycerides (TG) was 213.4 ± 183.1, High-Density Lipoprotein Cholesterol (HDL-C) was 39.8 ± 9.56 Low Density Lipoprotein Cholesterol (LDL-C) was 123.4 ± 46.9, whereas control group had the mean values for TC as 178.5 ± 37.5, TG as 161.1 ± 77.5, HDL-C as 43.8 ±10.6 and LDL-C as 117.7±33.8.
Conclusion: The study shows the elevated lipids in group with diabetes in comparison to the group with healthy individuals. Between the groups, there is a noticeable variation in the mean TG levels but slight difference in other lipids levels in both groups are alarming and indicating future risk of these non-diabetic individuals in getting diabetes and CVDs as well. Our findings are showing extreme need of education for lifestyle modifications and healthy diet plans in our society.
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