Histopathological Spectrum of Salivary Gland Lesions Reported at a Tertiary Care Hospital, Kharian Cantt, Pakistan
DOI:
https://doi.org/10.36283/ziun-pjmd14-3/042Keywords:
Biopsy, , Salivary Gland, Benign and Malignant NeoplasmsAbstract
Background: Salivary gland tumors, though uncommon, are clinically significant due to their diverse histological patterns, diagnostic complexity, and varying malignant potential. These tumors arise from both major and minor salivary glands, with the parotid gland being most frequently affected. Despite extensive global research, there is limited local epidemiological data in Pakistan. This study aimed to determine the morphological patterns and frequency of various salivary gland pathologies in biopsy specimens of patients at tertiary care hospital, Kharian Cantt, and to compare the findings with national and international data.
Methods: This retrospective cross-sectional study was conducted at the Department of Histopathology and Surgery, Tertiary care hospital, Kharian Cantt. Over 04 years from July 1, 2019, to June 30, 2023. A total of 50 patients of both genders with biopsy-confirmed salivary gland tumors were included using consecutive sampling. Clinical information was retrieved from pathology request forms. Biopsies were fixed in 10% formal saline, processed, and stained with hematoxylin and eosin. Histological evaluation was performed independently by two consultant histopathologists. Data were analyzed using SPSS version 22.
Results: Among the 50 patients, 64% were male and 36% female (male-to-female ratio 1.78:1). The most common presentation was a painless, firm glandular swelling (80%). The parotid gland was the most frequently involved site (64%). Benign tumors (84%) were more prevalent, with pleomorphic adenoma being the most common. Mucoepidermoid carcinoma was the most frequent malignant tumor.
Conclusion: Salivary gland tumors in this setting were predominantly benign, with male predominance and parotid gland involvement being most common.
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