Advancing Anesthesia Care and Challenges by Artificial Intelligence: A Prospective Study based on Systematic Review and Meta-Analysis

Authors

  • Mostafa Ahmed Abdellah Ahmed Frimley Health NHS Foundation Trust
  • Attiya Razzaq Gulab Devi Teaching Hospital , Lahore,Pakistan.
  • Amna Batool Fatima Memorial Hospital Lahore , Pakistan
  • Shaheer Nayyar Allama Iqbal Medical College, Jinnah Hospital Lahore, Pakistan.
  • Mahmood Ahmad Zahid Sheikh Khalifa Bin Zaid Hospital / CMH Rawalakot Azad Kashmir,Pakistan.
  • Muhammad Hussain University of Florence, Italy.

DOI:

https://doi.org/10.36283/ziun-pjmd14-3/063

Keywords:

Artificial Intelligence, Anesthesia, Perioperative Care, Clinical Decision Support Systems, Machine Learning

Abstract

Background: AI technologies remain essential in modern perioperative care, where they improve clinical decision outcomes and delivery of anesthesia. Health professionals need additional validation testing to determine the practical implementation of these systems for regular medical practice. This study aimed to evaluate the clinical effectiveness and diagnostic accuracy of AI-based tools in anesthesia and perioperative care.

Methods: This PRISMA-2020 based review included studies published till May 2025 on AI use in anesthesia and perioperative care with clinical outcomes. Two reviewers independently extracted data and assessed bias (Cochrane for RCTs, NOS for observational). Meta-analysis was done using RevMan 5.4.1 under a random-effects inverse-variance model. Results were reported as SMDs for clinical effectiveness and ORs for diagnostic accuracy. Heterogeneity (I²), subgroup, and sensitivity analyses were also performed.

Results: Seven research studies (5 as randomized controlled trials, 2 as observational ones) with 1,821 patients were found on inclusion. Anesthesia was implemented with the use of AI in the prediction of the diagnosis, monitoring of sedation, and facilitation of recovery. There were no significant differences in the outcomes of recovery (SMD: -0.36, 95% CI: -1.20 to 0.49). More diagnostic accuracy was achieved under the influence of AI (OR: 2.12; 95% CI: 1.05 to 4.27). The risk of bias was moderate or low.

Discussion: New evidence indicates that AI will transform perioperative care through automated decision support functions and outcome prediction solutions; however, a key limitation is the small number of eligible studies and high variability across clinical settings. Thus, standard evaluation standards and multicenter testing activities are necessary for this potential to become realizable.

Author Biographies

  • Mostafa Ahmed Abdellah Ahmed, Frimley Health NHS Foundation Trust

    Department of General Surgery,


  • Attiya Razzaq, Gulab Devi Teaching Hospital , Lahore,Pakistan.

    Department of Anesthesia,


  • Amna Batool, Fatima Memorial Hospital Lahore , Pakistan

    Department of Surgery, 

  • Shaheer Nayyar, Allama Iqbal Medical College, Jinnah Hospital Lahore, Pakistan.


    Department of Anesthesia & ICU,


  • Mahmood Ahmad Zahid, Sheikh Khalifa Bin Zaid Hospital / CMH Rawalakot Azad Kashmir,Pakistan.

    Department of Anesthesia,

  • Muhammad Hussain, University of Florence, Italy.

    Department of Biomedical Sciences,

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Published

2025-07-21

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How to Cite

1.
Ahmed MAA, Razzaq A, Batool A, Nayyar S, Zahid MA, Hussain M. Advancing Anesthesia Care and Challenges by Artificial Intelligence: A Prospective Study based on Systematic Review and Meta-Analysis. PJMD [Internet]. 2025 Jul. 21 [cited 2026 Jun. 4];14(3):446-5. Available from: https://ojs.zu.edu.pk/pjmd/article/view/3725

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