A New Era in Diabetes Treatment: Innovations Towards Remission
DOI:
https://doi.org/10.36283/PJMD13-1/002Abstract
Diabetes is a chronic health condition that affects millions of people globally. Medication, diet, and exercise can help manage the disease; however, recent breakthroughs in diabetes remission research bring hope for those living with the disease, paving the way for a new era in diabetes care with the potential for remission.
Exciting developments in diabetes research include using stem cells to replace damaged β-cells in the pancreas and stem cell transplantation and gene therapy, which have shown promise as potential cures for diabetes. Stem cells are also being studied for their potential to regenerate insulin-producing cells, leading to improved blood sugar control. Although in the early stages, these strategies have the potential to revolutionize diabetes treatment and offer a future free from the burdens of this debilitating disease.
References
Emerging diabetes therapies: Bringing back the β-cells. Molecular metabolism. 2022; 60, 101477. https://doi.org/10.1016/j.molmet.2022.101477.
Exosomes as Promising Nanostructures in Diabetes Mellitus: From Insulin Sensitivity to Ameliorating Diabetic Complications. International journal of nanomedicine. 2022; 17, 1229-1253. https://doi.org/10.2147/IJN.S350250.
An overview of advancements in closed-loop artificial pancreas system. Heliyon. 2022; 8(11), e11648. https://doi.org/10.1016/j.heliyon.2022.e11648.
Diabetes remission of bariatric surgery and nonsurgical treatments in type 2 diabetes patients who fail to meet the criteria for surgery: a systematic review and meta-analysis. BMC endocrine disorders. 2023; 23(1), 46. https://doi.org/10.1186/s12902-023-01283-9.
Pharmacological conversion of gut epithelial cells into insulin-producing cells lowers glycemia in diabetic animals. The Journal of clinical investigation. 2022; 132(24), e162720. https://doi.org/10.1172/JCI162720.
Durability of a primary care-led weight-management intervention for remission of type 2 diabetes: 2-year results of the DiRECT open-label, cluster-randomised trial. The lancet. Diabetes & endocrinology. 2019; 7(5), 344–355. https://doi.org/10.1016/S2213-8587(19)30068-3
Additional Files
Published
Issue
Section
License
Copyright (c) 2024 Pakistan Journal of Medicine and Dentistry
This work is licensed under a Creative Commons Attribution 4.0 International License.
This is an open-access article distributed under the terms of the CreativeCommons Attribution License (CC BY) 4.0 https://creativecommons.org/licenses/by/4.0/
How to Cite
