Serological Survey Of Respiratory Syncytial Virus (RSV) Among Children In Lorin North-Central, Nigeria.

Abstract

Background:

Respiratory Syncytial Virus(RSV) infection is a common worldwide problem. Childhood mortality and morbidity due to RSV is increasing. This study was aimed at determining the sero-prevalence rate of RSV IgG antibody and also to investigate some known risk factors for acquisition of RSV among children presenting with various forms of respiratory tract infections in Ilorin, Nigeria.

Methods:

total of 600 samples were collected from children (whose parent or guardian has consented) and analysed for anti RSV IgG antibody using ELISA. Information regarding socio-economic status and other demographic variables were recorded using well structured questionnaire.

Results:

A seroprevalence of 75% (450/600) was detected in the subjects. The seroprevalence among male was 72.70% and female 77.54% (P = 0.171). The age group 6-10 yrs had the highest prevalence of 80% while 0-5 yrs had 73.94%, with a highly significant association (P = 0.0001).

Conclusion:

This study showed high prevalence of RSV, with the highest prevalence in aged 6-10 years which suggests that, RSV is common among school-aged children. Thus the importance of RSV as an agent of respiratory tract infection in children is identified. Preventive measures should be adhered to in the control of the infection, as antiviral drugs are not readily available.