TO COMPARE THE EFFECTS OF ORAL MISOPROSTOL ALONE AND IN COMBINATION WITH INTRACERVICAL FOLEY’S IN INDUCTION OF LABOR

Abstract

ackground:

Induction of labor (IOL) is an obstetric intervention designed,usedin 20-30% of all pregnancies. The aim of this study was to assess the efficacy of oral misoprostol alone versus oral misoprostol and Foley’s catheter for IOL.

Methods:

All pregnant women age ≥18 years requiring induction of labor for various reasons and with unfavorable cervixes admitted in Ziauddin University Hospital Karachi are included in the study. Women were induced in “Group A” with an intracervical Foley’s catheter and tablet misoprostol 25 microgram given orally. In group B, women were given misoprostol 25 microgram tablets alone orally, subsequently every6 hourly for a maximum of four doses.

Results:

Normal vaginal delivery was significantly higher in group A (n=62, 59.6%) than that of group B (n=42, 40.4%) patients. Caesarean section was found higher in group B (n=25, 83.3%) patients than that of group A patients (n=516.7%; p-value <0.001). Frequency of meconium was found in 3 (14.3%) patients in group A while 18 (85.7%) in group B (p-value <0.001.

Conclusion:

The number of successful inductions within 24 hours was found better among women receiving oral misoprostol with intracervical Foley’s. Moreover, spontaneous vaginal delivery was also found higher in women receiving oral misoprostol only.