RELATIVE RISK OF DIABETES MELLITUS AMONG OBESE POPULATION

Authors

  • Umair Khalid Clinical Director, Jag One Physical Therapist Brooklyn, New York
  • Khuram Chaudry Freelancer, Physical Therapist Ontario
  • Hina Khuram Physiotherapist, The Mc Causland Hospital Ontario

Keywords:

Diabetes, obesity, odds ratio, risk, body mass index, prevalence

Abstract

Objective: Diabetes is more prevalent mainly in Asian population, but the incidence proportion and likelihood are still unknown due to lack of evidence and proper research, therefore in this research paper the main aim is to assess the relative risk of diabetes mellitus in obese people in Pakistan.

Methodology: A case control study was conducted on 233 participants including diabetic and non-diabetic. The participants were approached from different clinics and hospitals from Nov 2021 to April 2022 using convenient sampling technique. Participants’ age, body mass index and weight category were measured. The odds and relative risk ratio were calculated for diabetic patients in obese people.

Results: It was found that among the obese population, the odds of having diabetes were 3.85 times greater than that of non-obese adults whereas relative risk was also found to 2.17 times higher than that of non-obese population with the p-value <0.05.

Conclusions: The prevalence of obesity is higher in diabetic population as compared to non-diabetic individuals. This increases the chances of developing diabetes in obese population as compared to the individuals with normal weight.

References

Standl E, Khunti K, Hansen TB, Schnell O. The global epidemics of diabetes in the 21st century: Current situation and perspectives. Eur J Prev Cardiol. 2019 Dec 1;26(2_suppl):7-14.

Khan MA, Hashim MJ, King JK, Govender RD, Mustafa H, Al Kaabi J. Epidemiology of type 2 diabetes–global burden of disease and forecasted trends. J Epidemiol Glob Health. 2020 Mar;10(1):107.

Saeedi P, Petersohn I, Salpea P, Malanda B, Karuranga S, Unwin N, Colagiuri S, Guariguata L, Motala AA, Ogurtsova K, Shaw JE. Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas. Diabetes research and clinical practice. 2019 Nov 1;157:107843.

Centers for Disease Control and Prevention [Internet]. CDC. 2022 [cited 7 September 2022]. Available from: https://www.cdc.gov/diabetes/data/statistics-report/diagnosed-diabetes.html

Haw JS, Shah M, Turbow S, Egeolu M, Umpierrez G. Diabetes complications in racial and ethnic minority populations in the USA. Curr Diab Rep . 2021 Jan;21(1):1-8.

Aamir AH, Ul-Haq Z, Mahar SA, Qureshi FM, Ahmad I, Jawa A, Sheikh A, Raza A, Fazid S, Jadoon Z, Ishtiaq O. Diabetes Prevalence Survey of Pakistan (DPS-PAK): prevalence of type 2 diabetes mellitus and prediabetes using HbA1c: a population-based survey from Pakistan. BMJ open. 2019 Feb 1;9(2):e025300.

Meo SA, Zia I, Bukhari IA, Arain SA. Type 2 diabetes mellitus in Pakistan: Current prevalence and future forecast. J Pak Med Assoc. 2016 Dec 1;66(12):1637-42.

Harding JL, Pavkov ME, Magliano DJ, Shaw JE, Gregg EW. Global trends in diabetes complications: a review of current evidence. Diabetologia. 2019 Jan;62(1):3-16.

Newman JD, Schwartzbard AZ, Weintraub HS, Goldberg IJ, Berger JS. Primary prevention of cardiovascular disease in diabetes mellitus. J Am Coll Cardiol. 2017 Aug 15;70(7):883-93.

Aamir, A.H., Ul-Haq, Z., Fazid, S., Shah, B.H., Raza, A., Jawa, A., Mahar, S.A., Ahmad, I., Qureshi, F.M. and Heald, A.H., 2020. Type 2 diabetes prevalence in Pakistan: what is driving this? Clues from subgroup analysis of normal weight individuals in diabetes prevalence survey of Pakistan. Cardiovasc Endocrinol Metab., 9(4), p.159.

American Diabetes Association, 2019. 11. Microvascular complications and foot care: standards of medical care in diabetes—2019. Diabetes Care, 42(Supplement_1), pp.S124-S138.

EL-Ashmawy HM, Omar RE, Almazouq FM, Ahmed AM. Possible Role of Fatty Acid Binding Protein in Type 2 Diabetes and Peripheral Artery Disease. Egypt J Hosp Med. 2022 Oct 1;89(1):4270-2.

Sami W, Ansari T, Butt NS, Ab Hamid MR. Effect of diet on type 2 diabetes mellitus: A review. Int J Health Sci. 2017 Apr;11(2):65.

Rajput SA, Ashraff S, Siddiqui M. Diet and Management of Type II Diabetes Mellitus in the United Kingdom: A Narrative Review. Diabetology. 2022 Feb 7;3(1):72-8.

Jung CH, Son JW, Kang S, Kim WJ, Kim HS, Kim HS, Seo M, Shin HJ, Lee SS, Jeong SJ, Cho Y. Diabetes fact sheets in Korea, 2020: an appraisal of current status. Diabetes Metab J. 2021 Jan 13;45(1):1-0.

Chobot A, Górowska‐Kowolik K, Sokołowska M, Jarosz‐Chobot P. Obesity and diabetes—Not only a simple link between two epidemics. Diabetes/metabolism research and reviews. 2018 Oct;34(7):e3042.

Ramón-Arbués E, Martínez-Abadía B, Gracia-Tabuenca T, Yuste-Gran C, Pellicer-García B, Juárez-Vela R, Guerrero-Portillo S, Sáez-Guinoa M. Prevalence of overweight/obesity and its association with diabetes, hypertension, dyslipidemia and metabolic syndrome: a cross-sectional study of a sample of workers in Aragón, Spain. Nutr Hosp. 2019;36(1):51-9.

Malone JI, Hansen BC. Does obesity cause type 2 diabetes mellitus (T2DM)? Or is it the opposite?. Pediatr Diabetes. 2019;20(1):5-9.

Zucker I, Zloof Y, Bardugo A, Tsur AM, Lutski M, Cohen Y, Cukierman-Yaffe T, Minsky N, Derazne E, Tzur D, Melzer Cohen C. Obesity in late adolescence and incident type 1 diabetes in young adulthood. Diabetologia. 2022 Jun 5:1-0.

Fruh SM. Obesity: Risk factors, complications, and strategies for sustainable long‐term weight management. J Am Assoc Nurse Pract. 2017 Oct;29(S1):S3-14.

Mathur P, Leburu S, Kulothungan V. Prevalence, awareness, treatment and control of diabetes in India from the countrywide National NCD Monitoring Survey (NNMS). Public health frontier. 2022 Mar 14:205.

Abdullah A, Peeters A, de Courten M, Stoelwinder J. The magnitude of association between overweight and obesity and the risk of diabetes: a meta-analysis of prospective cohort studies. Diabetes Res Clin Pract. 2010 Sep 1;89(3):309-19.

Schnurr TM, Jakupović H, Carrasquilla GD, Ängquist L, Grarup N, Sørensen TI, Tjønneland A, Overvad K, Pedersen O, Hansen T, Kilpeläinen TO. Obesity, unfavourable lifestyle and genetic risk of type 2 diabetes: a case-cohort study. Diabetologia. 2020 Jul;63(7):1324-32.

Babu GR, Murthy GV, Ana Y, Patel P, Deepa R, Neelon SE, Kinra S, Reddy KS. Association of obesity with hypertension and type 2 diabetes mellitus in India: A meta-analysis of observational studies. World J Diabetes. 2018 Jan 1;9(1):40.

Glovaci D, Fan W, Wong ND. Epidemiology of diabetes mellitus and cardiovascular disease. Curr Cardiol Rep.2019 Apr;21(4):1-8.

Piché ME, Tchernof A, Després JP. Obesity phenotypes, diabetes, and cardiovascular diseases. Circ Res. 2020;126(11):1477-500.

La Sala L, Pontiroli AE. Prevention of diabetes and cardiovascular disease in obesity. Int J Mol Sci. 2020 Oct 31;21(21):8178.

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Published

2023-01-04

How to Cite

Khalid, U., Chaudry, K. ., & Khuram, H. . (2023). RELATIVE RISK OF DIABETES MELLITUS AMONG OBESE POPULATION. Pakistan Journal of Rehabilitation, 12(1), 93–98. Retrieved from http://ojs.zu.edu.pk/ojs/index.php/pjr/article/view/2095

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