• Zoha Sabir Demonstrator, Foundation University Institute of Rehabilitation Sciences (FUIRS)
  • Rimsha Hassan Student, Foundation University Institute of Rehabilitation Sciences (FUIRS)
  • Maria Bashir Student, Foundation University Institute of Rehabilitation Sciences (FUIRS)
  • Rida Akhtar Student, Foundation University Institute of Rehabilitation Sciences (FUIRS)
  • Ayesha Mehmood Student, Foundation University Institute of Rehabilitation Sciences (FUIRS)
  • Sana Bashir Senior Lecturer Foundation University Institute of Rehabilitation Sciences (FUIRS) Foundation University Islamabad (FUI)


Polycystic ovarian syndrome (PCOS), quality of life (QOL), social phobia, anxiety, infertility, depression


Background and Aim: Polycystic Ovarian Syndrome is an endocrine problem and its prevalence is on rise day by day in Pakistan, so the study aimed to determine occurrence of Anxiety and Depression among women with Polycystic Ovarian Syndrome and to check whether quality of life gets poor or not in relation to Polycystic Ovarian syndrome.

Methodology: It was a descriptive cross-sectional study, data was sampled using non-probability convenient sampling technique and analyzed on SPSS v. 20.0. Study was done on 150 participants, from Fauji Foundation Hospital and different private setups of Rawalpindi/Islamabad. Data was collected through Beck Depression Inventory, Beck Anxiety Inventory and SF-36 Questionnaires respectively.

Results: Mean age of the all patients was (24.7±5.9), and BMI was (23±5.1). Out of 150 participants, (40%) were normal, (20.60%) had mild mood disturbance, (17.3%) had moderate depression and (2.66%) had extreme depression. Similarly, (69.3%) of the participants had normal anxiety level and only (6.60%) had potentially concerning levels of anxiety. Mean and standard deviation for different domain of SF-Questionnaire was: physical functioning (70.1±25), physical health limitations were (50±34), emotional problems limitations (42.9±37), energy/fatigue (49.7±15.2), for emotional wellbeing was (55±14.7), for social functioning was (65±24.5), pain (65.6±23), and general health were (51.2±18) respectively.

Conclusion: Study concluded that occurrence of anxiety and depression among women with poly cystic ovarian syndromes was low, hence and their quality of life was not much affected.


Kabadayi Sahin E, Turan G, Neselioglu S, Can SS, Atagun MI. Thiol-disulphide homeostasis in patients with general anxiety disorder and panic disorder. Dusunen Adam The Journal of Psychiatry and Neurological Sciences. 2019;32(4):289.

Bandelow B, Michaelis S. Epidemiology of anxiety disorders in the 21st century. Dialogues in clinical neuroscience. 2015;17(3):327.

3. Zafar U, Memon Z, Moin K, Agha S, Hassan JA, Zehra D. Prevalence of PCOS with associated symptoms and complications at Tertiary Care Hospital of Karachi. Journal of Advances in Medicine and Medical Research. 2019:1-9.

Chaudhari AP, Mazumdar K, Mehta PD. Anxiety, depression, and quality of life in women with polycystic ovarian syndrome. Indian journal of psychological medicine. 2018;40(3):239-46.

Schuch FB, Vancampfort D, Richards J, Rosenbaum S, Ward PB, Stubbs B. Exercise as a treatment for depression: a meta-analysis adjusting for publication bias. Journal of psychiatric research. 2016;77:42-51.

Hart R. Generational health impact of PCOS on women and their children. Medical Sciences. 2019;7(3):49.

Kollmann M, Klaritsch P, Martins W, Guenther F, Schneider V, Herzog S, et al. Maternal and neonatal outcomes in pregnant women with PCOS: comparison of different diagnostic definitions. Human Reproduction. 2015;30(10):2396-403.

Akram M, Roohi N. Endocrine correlates of polycystic ovary syndrome in Pakistani women. J Coll Physicians Surg Pak. 2015;25(1):22-6.

Rao M, Broughton KS, LeMieux MJ. Cross-sectional Study on the Knowledge and Prevalence of PCOS at a Multiethnic University. Progress in Preventive Medicine. 2020;5(2):e0028.

Coutinho EA, Kauffman AS. The role of the brain in the pathogenesis and physiology of polycystic ovary syndrome (PCOS). Medical Sciences. 2019;7(8):84.

Arentz S, Smith CA, Abbott J, Bensoussan A. Perceptions and experiences of lifestyle interventions in women with polycystic ovary syndrome (PCOS), as a management strategy for symptoms of PCOS. BMC women's health. 2021;21(1):1-8.

Moghadam ZB, Fereidooni B, Saffari M, Montazeri A. Measures of health-related quality of life in PCOS women: a systematic review. International journal of women's health. 2018;10:397.

Greenwood EA, Yaffe K, Wellons MF, Cedars MI, Huddleston HG. Depression over the lifespan in a population-based cohort of women with polycystic ovary syndrome: longitudinal analysis. The Journal of Clinical Endocrinology & Metabolism. 2019;104(7):2809-19.

Koivuaho E, Laru J, Ojaniemi M, Puukka K, Kettunen J, Tapanainen J, et al. Age at adiposity rebound in childhood is associated with PCOS diagnosis and obesity in adulthood—longitudinal analysis of BMI data from birth to age 46 in cases of PCOS. International Journal of Obesity. 2019;43(7):1370-9.

Kakoly N, Moran L, Teede H, Joham A. Cardiometabolic risks in PCOS: a review of the current state of knowledge. Expert review of endocrinology & metabolism. 2019;14(1):23-33.

Mirghafourvand M, Charandabi SM-A, Aliasghari F. Predictors of depression in Iranian women with polycystic ovarian syndrome. Community mental health journal. 2018;54(8):1274-83.

Çoban ÖG, Tulacı ÖD, Adanır AS, Önder A. Psychiatric disorders, self-esteem, and quality of life in adolescents with polycystic ovary syndrome. Journal of pediatric and adolescent gynecology. 2019;32(6):600-4.

Standeven LR, Olson E, Leistikow N, Payne JL, Osborne LM, Hantsoo L. Polycystic Ovary Syndrome, Affective Symptoms, and Neuroactive Steroids: a Focus on Allopregnanolone. Current psychiatry reports. 2021;23(6):1-10.

Karjula S, Morin-Papunen L, Franks S, Auvinen J, Järvelin M-R, Tapanainen JS, et al. Population-based data at ages 31 and 46 show decreased HRQoL and life satisfaction in women with PCOS symptoms. The Journal of Clinical Endocrinology & Metabolism. 2020;105(6):1814-26.

Sukhapure M. Androgens and the Female Brain: The Relationship between Testosterone Levels, Depression, Anxiety, Cognitive Function, and Emotion Processing in Females with Polycystic Ovarian Syndrome: University of Otago; 2019.

Kogure GS, Lopes IP, Ribeiro VB, Mendes MC, Kodato S, Furtado CLM, et al. The effects of aerobic physical exercises on body image among women with polycystic ovary syndrome. Journal of affective disorders. 2020;262:350-8.

Greenwood E, Pasch L, Legro R, Cedars M, Huddleston H. Quality of life and depression in polycystic ovary syndrome. Fertility and Sterility. 2017;108(3):e64-e5.

Abdollahi L, Mirghafourvand M, Babapour JK, Mohammadi M. Effectiveness of cognitive-behavioral therapy (CBT) in improving the quality of life and psychological fatigue in women with polycystic ovarian syndrome: a randomized controlled clinical trial. Journal of Psychosomatic Obstetrics & Gynecology. 2019;40(4):283-93.

Kerchner A, Lester W, Stuart SP, Dokras A. Risk of depression and other mental health disorders in women with polycystic ovary syndrome: a longitudinal study. Fertility and sterility. 2009;91(1):207-12.

Azizi Kutenaee M, Amirjani S, Asemi Z, Taghavi S-A, Allan H, Kamalnadian S-N, et al. The impact of depression, self-esteem, and body image on sleep quality in patients with PCOS: a cross-sectional study. Sleep and Breathing. 2020;24(3):1027-34.



How to Cite

Sabir, Z., Hassan, R. ., Bashir, M., Akhtar, R., Mehmood, A. ., & Bashir, S. . (2022). OCCURRENCE OF ANXIETY, DEPRESSION AND QUALITY OF LIFE OF WOMEN WITH POLYCYSTIC OVARIAN SYNDROME. Pakistan Journal of Rehabilitation, 11(2), 76–82. Retrieved from http://ojs.zu.edu.pk/ojs/index.php/pjr/article/view/1489

Most read articles by the same author(s)

Obs.: This plugin requires at least one statistics/report plugin to be enabled. If your statistics plugins provide more than one metric then please also select a main metric on the admin's site settings page and/or on the journal manager's settings pages.