Hyperleukocytosis, a rare manifestation of autoimmune hemolytic anemia
Hyperleukocytosis and autoimmune hemolytic anemia
Keywords:
autoimmune hemolytic anemia, child, leukocytosis, mycoplasmaAbstract
Autoimmune hemolytic anemia (AIHA) is characterized by the binding of antibodies to red blood cell (RBC) surface antigens and initiate RBC destruction. White blood cell is usually normal and hyperleukocytosis is rare. The most common microorganism that has been associated with these hemolytic processes are Mycoplasma pneumoniae. Here, we repored a 4-year-old boy child who diagnosed AIHA by warm antibody testing with leukocytosis. The patient was treated with metylprednisolone, intravenous immunoglobulin and clarithromycin. During treatment, the leukocytosis returned to the normal range. The clinical condition and vital signs improved. The purpose of this study is to highlight hyperleukocytosis in AIHA caused by Mycoplasma pneumoniae.
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This is an open-access article distributed under the terms of the CreativeCommons Attribution License (CC BY) 4.0 https://creativecommons.org/licenses/by/4.0/