Frequency of Endometriosis on Diagnostic Laparoscopy in Females with Secondary Infertility
DOI:
https://doi.org/10.36283/PJMD13-2/010Keywords:
Endometriosis, Infertility, LaparoscopyAbstract
Background: For endometriosis, one of the most common chronic diseases encountered in gynecological outdoors, laparoscopy, is considered as a gold-standard diagnostic tool because direct visualization of endometriotic lesions enables the medical practitioner to provide recommendations for future therapy. This study aimed to determine the frequency of endometriosis on diagnostic laparoscopy in females with secondary infertility.
Methods: A cross-sectional study among 92 females was conducted at the Department of Obstetrics & Gynecology, Sir Ganga Ram Hospital, Lahore, from December 2022 to June 2023. Females aged 20-45 years, presenting with secondary infertility and subjected to diagnostic laparoscopy were analyzed using a non-probability, consecutive sampling technique. Data regarding the age, BMI, residence, parity, duration of infertility, and menstrual cycle were recorded. The findings of laparoscopic diagnosis regarding endometriosis were labeled. SPSS vr26 was used. The chi-square test was used to see the impact of effect modifiers on the frequency of endometriosis, taking p≤0.05 as significant.
Results: Out of a total of 92 females, (mean age 36.66±5.41years), 65 (70.7%) females were aged between 35-45 years. The mean BMI was 24.6±3.2 kg/m2 and the secondary infertility mean duration was 22.05±6.04 months while the mean parity was 2.09±0.82. Endometriosis was diagnosed among 28 (30.4%) females, in which 16 (57.1%) had a duration of infertility above 2 years (p=0.013) with parity <3 (p=0.761).
Conclusion: Using diagnostic laparoscopy, the frequency of endometriosis was found significant among females having secondary infertility. Laparoscopic evaluation can be helpful in the timely diagnosis and management of secondary infertility.
References
Katole A, Saoji AV. Prevalence of Primary Infertility and its Associated Risk Factors in Urban Population of Central India: A Community-Based Cross-Sectional Study. Indian J Community Med. 2019;44(4):337-341. doi: 10.4103/ijcm.IJCM_7_19
Katib AA, Al-Hawsawi K, Motair W, Bawa AM. Secondary infertility and the aging male, overview. Cent European J Urol. 2014;67(2):184-188. doi:10.5173/ceju.2014.02. art13
Siraj A, Choudry A, Naseer S, Humayun P, Khan S. Causes of infertility in females: evaluated by diagnostic laparoscopy at a tertiary care center. Pak Armed Forces Med J. 2015;65(5):600-603.
Carson SA, Kallen AN. Diagnosis and Management of Infertility: A Review. JAMA. 2021;326(1):65-76. doi:10.1001/jama.2021.4788
Thable A, Duff E, Dika C. Infertility management in primary care. Nurse Pract. 2020;45(5):48-54. doi: 10.1097/01.NPR.0000660356.18430.0a
Appleyard TL, Mann CH, Khan KS. Guidelines for the management of pelvic pain associated with endometriosis: a systematic appraisal of their quality. BJOG. 2006;113(7):749-757. doi: 10.1111/j.1471-0528.2006.00937.x.
Guo SW, Wang Y. The prevalence of endometriosis in women with chronic pelvic pain. Gynecol Obstet Invest. 2006;62(3):121-130. doi: 10.1159/000093019.
Balasch J, Creus M, Fábregues F, Carmona F, Ordi J, Martinez-Román S, Vanrell JA. Visible and non-visible endometriosis at laparoscopy in fertile and infertile women and patients with chronic pelvic pain: a prospective study. Hum Reprod. 1996;11(2):387-391. doi: 10.1093/humrep/11.2.387.
Farquhar C M. Endometriosis. BMJ 2000; 320:1449. doi:10.1136/bmj.320.7247.1449
Allaire C, Bedaiwy MA, Yong PJ. Diagnosis and management of endometriosis. CMAJ. 2023;195(10):E363-E371. doi:10.1503/cmaj.220637
Jain G, Khatuja R, Juneja A, Mehta S. Laparoscopy:as a first line diagnostic tool for infertility evaluation. J Clin Diagn Res. 2014;8(10): OC01-OC2. doi:10.7860/JCDR/2014/9822.4929
Shetty S, Shetty H. Diagnostic Laparoscopy in Infertility-A Retrospective study. Int J Biomed Res 2013;4(7):343-348.
Akalewold M, Yohannes GW, Abdo ZA, Hailu Y, Negesse A. Magnitude of infertility and associated factors among women attending selected public hospitals in Addis Ababa, Ethiopia: a cross-sectional study. BMC Womens Health. 2022;22(1):11. doi:10.1186/s12905-022-01601-8
Eskenazi B, Warner ML. Epidemiology of endometriosis. Obstet Gynecol Clin North Am. 1997;24(2):235-258. doi:10.1016/s0889-8545(05)70302-8
Vannuccini S, Clemenza S, Rossi M, Petraglia F. Hormonal treatments for endometriosis: The endocrine background. Rev Endocr Metab Disord. 2022;23(3):333-355. doi:10.1007/s11154-021-09666-w
Filip L, Duică F, Prădatu A, Cretoiu D, Suciu N, Cretoiu SM, et al. Endometriosis Associated Infertility: A Critical Review and Analysis on Etiopathogenesis and Therapeutic Approaches. Medicina (Kaunas). 2020;56(9):460. doi:10.3390/medicina56090460
Bonavina G, Taylor HS. Endometriosis-associated infertility: From pathophysiology to tailored treatment. Front Endocrinol (Lausanne). 2022; 13:1020827. doi:10.3389/fendo.2022.1020827
Mehmud G, Akhtar T, Sadia S. Endometriosis: frequency and correlation between symptomatology and disease stage. J Coll Physicians Surg Pak. 2007;17(4):199-202.
Memon E, Sumreen M, Nadia, Nazia, Baloch H. Frequency of endometriosis found on laparoscopic examination among females with subfertility. Professional Med J 2022;29(2):206-211. doi: 10.29309/TPMJ/2022.29.02.6542
Shabir NA, Rafique R, Raja SA. Frequency of endometriosis among Infertile Women on diagnostic laparoscopy. Int J Pathol. 2018;16(4):90-94.
Levy L, Tsaltas J. Recent advances in benign gynecological laparoscopic surgery. Fac Rev. 2021; 10:60. doi:10.12703/r/10-60
Tabbsum T, Nafees S, Hayes T, Mehmood HS, Sattar A. Frequency of endometriosis in females with infertility undergoing diagnostic laparoscopy: Endometriosis in females with Infertility. Pak J Health Sci. 2022;3(03)13–16. doi: 10.54393/pjhs.v3i03.65
Prescott J, Farland LV, Tobias DK, et al. A prospective cohort study of endometriosis and subsequent risk of infertility. Hum Reprod. 2016;31(7):1475-1482. doi:10.1093/humrep/dew085
Pal M, Devgun P, Chalana H, Kaur H, Biswas A, Sen S. A study of prevalence and socio-demographic profile of infertile couples in field practice area of a tertiary care centre, Amritsar, Punjab, India. Inter J Community Med Public Health 2017;3(6):1472-1476. doi:10.18203/2394-6040.ijcmph20161613
Verma K, Baniya GC. A comparative study of depression among infertile and fertile women. Int J Res Med Sci 2017;4(8):3459-3465. doi:10.18203/2320-6012.ijrms20162312
Kumar D. Prevalence of female infertility and its socio-economic factors in tribal communities of Central India. Rural Remote Health. 2007;7(2):456.
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