Targeted Thrombolytic Enzymes Delivery

Authors

  • Taimoor Hassan School of Pharmacy & School of Medicine, Changzhou University, Jiangsu, China

DOI:

https://doi.org/10.36283/PJMD11-2/001

Abstract

The intravascular delivery of thrombolytic medicines is required due to the small molecular sizes of the medications, resulting in systemic effects and the induction of the lytic state. Although the dose of tPA is higher than that encountered by a healthy organism, it is only partly provided (0.9 mg/kg for stroke, not more than 90 mg and100 mg for myocardial infarction) due to the rapid degradation of tPA upon delivery. Its blood lodging period is just a few minutes, as opposed to the newer type (Tenecteplase, TNKase®), which has a somewhat longer time to lodge blood. 

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Published

2023-11-20

How to Cite

Hassan, T. (2023). Targeted Thrombolytic Enzymes Delivery. Pakistan Journal of Medicine and Dentistry, 11(2), 1–2. https://doi.org/10.36283/PJMD11-2/001

Issue

Vol. 11 No. 2 (2022): Vol. 11 No. 2(2022): Pakistan Journal of Medicine and Dentistry, 11-2, April - June 2022

Section

Editorial

License

Copyright (c) 2022 Pakistan Journal of Medicine and Dentistry

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

This is an open-access article distributed under the terms of the CreativeCommons Attribution License (CC BY) 4.0 https://creativecommons.org/licenses/by/4.0/

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