CLINICAL PRESENTATION, RISK FACTORS AND ETIOLOGY OF LUNG ABSCESS

Abstract

Background:

A lung abscess is characterized by a necrotic lesion with marked cavitation and exudate within the lung parenchyma. The objective of this study was to identify the most common causative agent of lung abscess within our target population.

Methods:

Retrospective data from two consecutive years was obtained from the pulmonology department at Jinnah Postgraduate Medical Centre, one of Pakistan’s largest public hospitals. A total of 41 cases of lung abscess were identified on the bases of clinical, radiological and microbiological evidence. These cases were then analysed to establish a link between the incidence of abscess and key factors such as the most common causative organism, the correlation of age and gender and the location within the lung parenchyma.

Results:

Sputum for routine culture and sensitivity (C/S) showed Pseudomonas Aeruginosa (29.3%) as the most common causative organism. Correlation between abscess and risk factors such as history of smoking (65.9%), poor oral hygiene (56.1%), diabetes (43.9%) and alcoholism (14.6%) have been discussed and compared to previous publications. The frequency of common symptoms such as productive cough (90.2%), fever (82.9%) hemoptysis (58.5%) and clubbing of fingers (46.3%) have been analysed and a contrast is drawn in some instances between our obtained values and pre-existing data. The most common site of involvement is the lower lobe of the right lung (51.2%).

Conclusion:

Pseudomonas Aeruginosa was found to be the most common causative bacteria within the population for lung abscess while smoking was shown to be the most common risk factor.